a book, especially a large, heavy, scholarly one Meaning, pronunciation, example sentences, and more from Oxford Dictionaries. tome meaning, definition, what is tome: a large, heavy book. Learn more. Tomes definition, a book, especially a very heavy, large, or learned book. See more. From Wikipedia, the free encyclopedia. Personal tools Not logged in Talk Contributions Create account Log in. Originally "a single volume of a multi-volume work;" sense of "a large book" kiezking attested from s. Other Publishing Terms annotatedreadfulemendexpurgatefactoidjumplobster shiftredactionreferee. Originally "a single volume of tomes multi-volume work;" sense of "a large book" is attested from s. Archaic words have a charm that never fades away, from French sounding to wondrously mysterious ones. Name That Thing Tomes your visual vocabulary with our question challenge!